Simultaneous profiling of spatial gene expression and chromatin accessibility during mouse brain development |
Fuqing Jiang,Xin Zhou,Yingying Qian,Miao Zhu,Li Wang,Zhuxia Li,Qingmei Shen,Minhan Wang,Fangfang Qu,Guizhong Cui,Kai Chen,Guangdun Peng |
2023 |
Nature Methods |
Transforming Growth Factor Beta Promotes Inflammation and Tumorigenesis in Smad4-Deficient Intestinal Epithelium in a YAP-Dependent Manner |
Liansheng Liu,Yalong Wang,Shicheng Yu,Huidong Liu,Yehua Li,Shan Hua,Ye-Guang Chen |
2023 |
Advanced Science |
T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity |
Yuanbin Cui,Tingjie Yuan,Ying Wang,Diwei Zheng,Le Qin,Shanglin Li,Zhiwu Jiang,Shouheng Lin,Wenjing Guo,Zhi Wang,Zhaoduan Liang,Yi Li,Yao Yao,Xingguo Liu,Qiannan Tang,Hai-Yan Tu,Xu-Chao Zhang, Zhaoyang Tang,Nathalie Wong,Zhenfeng Zhang,Dajiang Qin,Jean Paul Thiery,Kailin Xu,Peng Li |
2023 |
Cell Reports |
A Rationally Designed CRISPR/Cas12a Assay Using a Multimodal Reporter for Various Readouts |
Jean de Dieu Habimana,Omar Mukama,Obed Boadi Amissah,Yirong Sun,Eric Karangwa,Yujie Liu,Samson Mugisha,Na Cheng,Ling Wang,Jianlin Chen,Sihao Deng,Rongqi Huang,Zhiyuan Li |
2023 |
Analytical Chemistry |
Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex |
Shuqi Dong,Huadong Li,Meilin Wang,Nadia Rasheed,Binqian Zou,Xijie Gao,Jiali Guan,Weijie Li,Jiale Zhang,Chi Wang,Ningkun Zhou,Xue Shi,Mei Li,Min Zhou,Junfeng Huang,He Li,Ying Zhang,Koon Ho Wong,Xiaofei Zhang,William Chong Hang Chao,Jun He |
2023 |
Cell Research |
Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription |
Jingke Xie,Zhenpeng Zhuang,Shixue Gou,Quanjun Zhang,Xia Wang,Ting Lan,Meng Lian,Nan Li,Yanhui Liang,Zhen Ouyang,Yinghua Ye,Han Wu,Liangxue Lai,Kepin Wang |
2023 |
Nucleic Acids Research |
Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation |
Jiaowei Wang,Wenguang Xie,Nan Li,Wenjuan Li,Zhishuai Zhang,Nana Fan,Zhen Ouyang,Yu Zhao,Chengdan Lai,Hao Li,Mengqi Chen,Longquan Quan,Yunpan Li,Yu Jiang,Wenqi Jia,Lixin Fu,Md. Abdul Mazid, Yanling Zhu,Patrick H. Maxwel,Guangjin Pan,Miguel A. Esteban,Zhen Dai,Liangxue Lai |
2023 |
Cell Stem Cell |
Nuclear localization of TET2 requires β-catenin activation and correlates with favourable prognosis in colorectal cancer |
Changpeng Li,Jingcai He,Fei Meng,Fuhui Wang,Hao Sun,Huizhong Zhang,Linna Dong,Mengdan Zhang,Qiaoran Xu,Lining Liang,Yuan Li,Tingting Yang,Meiai He,Tao Wang,Jiechun Lin,Jiaqi Sun,Qiuling Huang, Lin Guo,Xiaofei Zhang,Shijuan Mai,Hui Zheng |
2023 |
Cell Death & Disease |
Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte |
Shiting Zhao,Tao Nie,Lei Li,Qiaoyun Long,Ping Gu,Yuwei Zhang,Wei Sun,Zexin Lin,Qing Liu,Yue Qi,Wei Wang,Mengyuan Xie,Kerry Loomes,Chenleng Cai,Donghai Wu,Hannah Xiaoyan Hui |
2023 |
Advanced Science |
1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells |
Shiting Zhao,Abdelsalam S Ali,Xinyu Kong,Yan Zhang,Xiaomin Liu,Melissa A Skidmore,Craig M Forsyth,G Paul Savage,Donghai Wu,Yong Xu,Craig L Francis |
2023 |
European Journal of Medicinal Chemistry |
DEP2: an upgraded comprehensive analysis toolkit for quantitative proteomics data |
Zhenhuan Feng,Peiyang Fang,Hui Zheng,Xiaofei Zhang |
2023 |
Bioinformatics |
MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy |
Xue Shi, Wenfeng Wu, Zhenhuan Feng, Peiyang Fan, Ruona Shi, Xiaofei Zhang |
2023 |
Cell Reports |
SARS-CoV-2 induces cardiomyocyte apoptosis and inflammation but can be ameliorated by ACE inhibitor Captopril |
Xiaohan Huang,Wenxia Fan,Jing Sun,Jiaqing Yang,Yanjun Zhang,Qian Wang?Pingchao Li,Yudi Zhang,Shengnan Zhang,Heying Li,Jianhua Wang,Liqiang Feng,Jincun Zhao,Ling Chen,Linbing Qu |
2023 |
Antiviral Research |
Rational Design, Synthesis and Biological Evaluation of Benzo[d]isoxazole Derivatives as Potent BET Bivalent Inhibitors for Potential Treatment of Prostate Cancer |
Junhua Li, Run Zhu, Xiaoxi Zhuang, Cheng Zhang, Hui Shen, Xishan Wu, Maofeng Zhang, Cen Huang, Qiuping Xiang, Linxiang Zhao, Yong Xu, Yan Zhang |
2023 |
Bioorganic Chemistry |
BRPF1 bridges H3K4me3 and H3K23ac in human embryonic stem cells and is essential to pluripotency |
Cong Zhang, Huaisong Lin, Yanqi Zhang, Qi Xing, Jingyuan Zhang, Di Zhang, Yancai Liu, Qianyu Chen, Tiancheng Zhou, Junwei Wang, Yongli Shan, Guangjin Pan |
2023 |
iScience |