| Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency |
Hao Sun,Xiao Yang,Lining Liang,Mengdan Zhang,Yuan Li,Jinlong Chen,Fuhui Wang,Tingting Yang,Fei Meng,Xiaowei Lai,Changpeng Li,Jingcai He,Meiai He,Qiaoran Xu，Qian Li,Lilong Lin,Duanqing Pei,Hui Zheng |
2020 Apr; |
EMBO Journal |
| Lack of AKAP3 disrupts integrity of subcellular structure and proteome of mouse sperm and causes male sterility |
Kaibiao Xu,Lele Yang,Lan Zhang,Huayu Qi |
2020 Jan; |
Development |
| R-loops coordinate with SOX2 in regulating reprogramming to pluripotency |
Yaoyi Li,Yawei Song,Wei Xu,Qin Li,Xinxiu Wang,Kuan Li,Juehan Wang,Zicong Liu,Sergiy Velychko,Rong Ye,Qing Xia,Lei Wang,Rong Guo,Xiaotao Dong,Zhikai Zheng,Yushuang Dai,Haojie Li,Mingze Yao,Yuanchao Xue, Hans R. Sch？ler,Qianwen Sun,Hongjie Yao |
2020 Jun; |
Science Advances |
| BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling |
Shengyong Yu,Chunhua Zhou,Shangtao Cao,Jiangping He,Baomei Cai,Kaixin Wu,Yue Qin,Xingnan Huang,Lizhan Xiao,Jing Ye,Shuyang Xu,Wenxiu Xie,Junqi Kuang,Shilong Chu,Jing Guo,He Liu,Wei Pang,Lin Guo,Mengying Zeng,Xiaoshan Wang,Rongping Luo,Chen Li,Guoqing Zhao,Bo Wang,Linlin Wu,Jiekai Chen,Jing Liu,Duanqing Pei |
2020 Jun; |
Nature Cell Biology |
| OPA1-Exon4b Binds to mtDNA D-Loop for Transcriptional and Metabolic Modulation, Independent of Mitochondrial Fusion |
Liang Yang,Haite Tang,Xiaobing Lin,Yi Wu,Sheng Zeng,Yongzhang Pan,Yukun Li,Ge Xiang,Yi-Fang Lin,Shi-Mei Zhuang,Zhiyin Song,Yiguo Jiang,Xingguo Liu |
2020 Apr; |
Frontiers in Cell and Developmental Biology |
| Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response |
Xuefeng Niu,Qihong Yan,Zhipeng Yao,Fan Zhang,Linbing Qu,Chunlin Wang,Chengrui Wang,Hui Lei,Chaoming Chen,Renshan Liang,Jia Luo,Qian Wang,Lingzhai Zhao,Yudi Zhang,Kun Luo,Longyu Wang,Hongkai Wu,Tingting Liu,Pingchao Li,Zhiqiang Zheng,Yee Joo Tan,Liqiang Feng,Zhenhai Zhang,Jian Han,Fuchun Zhang,Ling Chen |
2020 Jan; |
Emerging Microbes & Infections |
| Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2 |
Linlin Hou,Yuanjie Wei,Yingying Lin,Xiwei Wang,Yiwei Lai,Menghui Yin,Yanpu Chen,Xiangpeng Guo,Senbin Wu,Yindi Zhu,Jie Yuan,Muqddas Tariq,Na Li,Hao Sun,Huating Wang,Xiaofei Zhang,Jiekai Chen,Xichen Bao,Ralf Jauch |
2020 Apr; |
Nucleic Acids Research |
| Naloxone regulates the differentiation of neural stem cells via a receptor-independent pathway |
Jinlong Chen,Lining Liang,Yuan Li,Yixin Zhang,Mengdan Zhang,Tingting Yang,Fei Meng,Xiaowei Lai,Changpeng Li,Jingcai He,Meiai He,Qiaoran Xu,Qian Li,Ping‐Yee Law,Horace H. Loh,Duanqing Pei,Hao Sun,Hui Zheng |
2020 Apr; |
FASEB Journal |
| Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway |
Lining Liang,Jinlong Chen,Yuan Li,Xiaowei Lai,Hao Sun,Changpeng Li,Mengdan Zhang,Tingting Yang,Fei Meng,Ping-Yee Law,Horace H. Loh,Hui Zheng |
2020 Mar; |
Cell Reports |
| Topology-dependent, bifurcated mitochondrial quality control under starvation |
Yanshuang Zhou,Qi Long,Hao Wu,Wei Li,Juntao Qi,Yi Wu,Ge Xiang,Haite Tang,Liang Yang,Keshi Chen,Linpeng Li,Feixiang Bao,Heying Li,Yaofeng Wang,Min Li,Xingguo Liu |
2020 Mar; |
Autophagy |
| JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells |
Yongli Shan,Yanqi Zhang,Yuan Zhao,Tianyu Wang,Jingyuan Zhang,Jiao Yao,Ning Ma,Zechuan Liang,Wenhao Huang,Ke Huang,Tian Zhang,Zhenghui Su,Qianyu Chen,Yanling Zhu,Chuman Wu,Tiancheng Zhou,Wei Sun,Yanxing Wei,Cong Zhang,Chenxu Li,Shuquan Su,Baojian Liao,Mei Zhong,Xiaofen Zhong,Jinfu Nie,Duanqing Pei,Guangjin Pan |
2020 Jan; |
Nature Communications |
| SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States |
Kaixin Wu,He Liu,Yaofeng Wang,Jiangping He,Shuyang Xu,Yaping Chen,Junqi Kuang,Jiadong Liu,Lin Guo,Dongwei Li,Ruona Shi,Li Shen,Yangming Wang,Xiaofei Zhang,Jie Wang,Duanqing Pei,Jiekai Chen |
2020 Jan; |
Cell Reports |
| Heterochromatin loosening by the Oct4 linker region facilitates Klf4 binding and iPSC reprogramming |
Keshi Chen,Qi Long,Guangsuo Xing,Tianyu Wang,YiWu,Linpeng Li,Juntao Qi,Yanshuang Zhou,Bochao Ma,Hans R Sch？ler,Jinfu Nie,Duanqing Pei,Xingguo Liu |
2020 Jan; |
EMBO Journal |
| Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors |
Rongqun Guo,Fangxiao Hu,Qitong Weng,Cui Lv,Hongling Wu,Lijuan Liu,Zongcheng Li,Yang Zeng,Zhijie Bai,Mengyun Zhang,Yuting Liu,Xiaofei Liu,Chengxiang Xia,Tongjie Wang,Peiqing Zhou,Kaitao Wang,Yong Dong, Yuxuan Luo,Xiangzhong Zhang,Yuxian Guan,Yang Geng,Juan Du,Yangqiu Li,Yu Lan,Jiekai Chen,Bing Liu,Jinyong Wang |
2020 Jan; |
Cell Research |
| Discovery of the First Low Nanomolar Liver Receptor Homolog-1 (LRH-1) Agonist |
Xishan Wu,Yan Zhang,Yong Xu |
2019 Dec; |
Journal of Medicinal Chemistry |
