| Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators |
Shu Wei, Qingjian Zou, Sisi Lai, Quanjun Zhang, Li Li, Quanmei Yan,Xiaoqing Zhou, Huilin Zhong， Liangxue Lai |
2016 Jan |
Scientific Reports |
| Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering |
Yi Yang, Kepin Wang, Han Wu, Qin Jin, Degong Ruan, Zhen Ouyang, Bentian Zhao, Zhaoming Liu, Yu Zhao, Quanjun Zhang, Nana Fan, Qishuai Liu, Shimei Guo，Lei Bu, Yong Fan, Xiaofang Sun, Xiaoping Li, Liangxue Lai |
2016 Apr |
Journal of Molecular Cell Biology |
| Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities |
Jinhong Bai, Chenzhong Liao,Yanghan Liu, Xiaochu Qin, Jiaxuan Chen, Yatao Qiu,Dongguang Qin, Zheng Li,Zheng-Chao Tu,Sheng Jiang |
2016 Jun |
Journal of Medicinal Chemistry |
| Pd-Catalyzed C(sp2)-H carbonylation of 2-benzylpyridines for the synthesis of pyridoisoquinolinones |
Zeqiang Xie, Shuang Luo,Qiang Zhu |
2016 Oct |
Chemical Communications |
| A metal-free synthesis of 2-aminobenzothiazoles through aminyl radical addition to aryl isothiocyanates |
Yimiao He, Jing Li, Shuang Luo, Jinbo Huang,Qiang Zhu |
2016 Jun |
Chemical Communications |
| Transcriptional Control of Somatic Cell Reprogramming |
Yan Xu, Meng Zhang, Wenjuan Li, Xihua Zhu, Xichen Bao, Baoming Qin, Andrew P. Hutchins, Miguel A. Esteban |
2016 Apr |
Trends in Cell Biology |
| Gadd45a is a heterochromatin relaxer that enhances iPS cell generation |
Keshi Chen, Qi Long, Tao Wang, Danyun Zhao, Yanshuang Zhou, Juntao Qi, Yi Wu, Shengbiao Li, Chunlan Chen, Xiaoming Zeng, Jianguo Yang, Zisong Zhou, Weiwen Qin, Xiyin Liu, Yuxing Li, Yingying Li, Xiaofen Huang, Dajiang Qin, Jiekai Chen, Guangjin Pan, Hans R Sch？ler, Guoliang Xu, Xingguo Liu, Duanqing Pei |
2016 Nov |
EMBO Reports |
| Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis |
Ke Huang, Jiao Gao, Juan Du, Ning Ma, Yanling Zhu, Pengfei Wu,Tian Zhang,Wenqian Wang,Yuhang Li, Qianyu Chen, Andrew Paul Hutchins, Zhongzhou Yang, Yi Zheng,Jian Zhang, Yongli Shan, Xuejia Li, Baojian Liao, Jiajun Liu, Jinyong Wang, Bing Liu,Guangjin Pan |
2016 Nov |
Stem Cell Reports |
| Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors |
Zhen Wang, Huan Bian, Sergio G. Bartual, Wenting Du, Jinfeng Luo, Hu Zhao, Shasha Zhang, Cheng Mo, Yang Zhou, Yong Xu, Zhengchao Tu, Xiaomei Ren, Xiaoyun Lu, Rolf A. Brekken, Libo Yao, Alex N. Bullock, Jin Su, Ke Ding |
2016 Jun |
Journal of Medicinal Chemistry |
| 4-Oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as New Axl Kinase Inhibitors |
Li Tan, Zhang Zhang, Donglin Gao, Jinfeng Luo, Zheng-Chao Tu, Zhengqiu Li, Lijie Peng, Xiaomei Ren,Ke Ding |
2016 Jul |
Journal of Medicinal Chemistry |
| CRISPR/Cas9 Facilitates Investigation of Neural Circuit Disease using Human iPSCs: Mechanism of Epilepsy Caused by an SCN1A Loss-of-function Mutation |
Liu J, Gao C, Chen W, Ma W, Deng S, Li X, Shi Y, Zhang H, Zhang L, Long Y, Xu H, Guo X, Lai L, Pan G, Chen Y, Liao W, Li Z |
2016 Jan |
Zhiyuan Li |
| Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models |
Manman Deng, Zhiwu Jiang, Yin Li, Yong Zhou, Jie Li, Xiangmeng Wang,Yao Yao, Weiguang Wang, Peng Li, Bing Xu |
2016 Dec |
oncotarget |
| Vaccine Engineering with Dual-Functional Mineral Shell: A Promising Strategy to Overcome Preexisting Immunity |
Xiaoyu Wang, Caijun Sun, Pingchao Li, Tongjin Wu, Hangyu Zhou, Dong Yang,Yichu Liu, Xiuchang Ma,Zhiyong Song, Qinggong Nian, Liqiang Feng,Chengfeng Qin, Ling Chen,Ruikang Tang |
2016 Jan |
Advanced Materials |
| Potent neutralizing monoclonal antibodies against Ebola virus infection |
Qi Zhang, Miao Gui, Xuefeng Niu, Shihua He, Ruoke Wang, Yupeng Feng, Andrea Kroeker, Yanan Zuo, Hua Wang, Ying Wang, Jiade Li, Chufang Li, Yi Shi, Xuanling Shi, George F. Gao, Ye Xiang, Xiangguo Qiu, Ling Chen,Linqi Zhang |
2016 May |
Scientific Reports |
| Simple and versatile synthetic polydopamine-based surface supports reprogramming of human somatic cells and long-term self-renewal of human pluripotent stem cells under defined conditions |
Ping Zhou,Fujian Wu, Tiancheng Zhou, Xiujuan Cai, Siqi Zhang, Xiaohong Zhang, Qiuhong Li, Yongliang Li, Yunfei Zheng, Mengke Wang, Feng Lan, Guangjin Pan, Duanqing Pei, Shicheng Wei |
2016 May |
Biomaterials |
