論文
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中文論文題目: | Expedient Construction of the Ziegler Intermediate Useful for the Synthesis of Forskolin via Consecutive Rearrangements |
英文論文題目: | Expedient Construction of the Ziegler Intermediate Useful for the Synthesis of Forskolin via Consecutive Rearrangements |
作者: | Heping Ye, Gang Deng, Jun Liu, and Fayang Qiu. |
論文出處: | |
刊物名稱: | Organic Letters |
年: | 2009 |
卷: | 11 |
期: | 23 |
頁: | 5442-5444 |
聯係作者: | Fayang Qiu |
收錄類別: | |
影響因子: | 5.128 |
摘要: | The Ziegler intermediate, useful for the total synthesis of forskolin, was synthesized in 10 reaction steps starting from commercially available α-ionone. This highly efficient synthesis relies on the success of two consecutive highly regio- and stereoselective rearrangements. The current synthesis has not only established an efficient synthetic route to access the Ziegler intermediate but it has also paved a way to the structural optimization of forskolin. |
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