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專家人才

  • 姓名:尹夢回
  • 性別:
  • 職稱:副研究員
  • 學曆:
  • 電話:020-32015234
  • 傳真:
  • 電子郵件:yin_menghui@gibh.ac.cn
  • 通訊地址廣州蘿崗區科學城開源大道190號

    簡曆:

  •   2001/09-2005/06西南農業大學農學與生命科學學院學士

    2005/09-2008/06西南大學生物技術中心碩士

    2008/09-2012/06中國科學技術大學生命科學學院博士

    2012/07-betway体育下载 ,化學與生物學所,助理研究員、副研究員

    研究領域:

  • 非編碼RNA在腫瘤中的功能研究,RNARNA結合蛋白的相互作用在基因表達調控中的機理研究。

    承擔科研項目情況:

    社會任職:

    獲獎及榮譽:

    代表論著:

  • 1.Yin M#, Ren X#, Zhang X, Luo Y, Wang G, Huang K, Feng S, Bao X, Huang K, He X, Liang P, Wang Z, Tang H, He J*, Zhang B*. Selective killing of lung cancer cells by miRNA-506 molecule through inhibiting NF-κB p65 to evoke reactive oxygen species generation and p53 activation.Oncogene,, 2015, 34(6):691

    2.Xiaoshuai Ren,Menghui Yin, Xin Zhang, Zhe Wang, Shipeng Feng, Guoxin Wang,Yingjun Luo, Peizhou Liang, Xiuqun Yang, Jianxing He* and Biliang Zhang*, Tumor-suppressive microRNA-449a induces growth arrest and senescence by targetingE2F3 in human lung cancer cells. Cancer Letters, 344(2),195-203, 2014.

    3.Bao X, Wu H, Zhu X, Guo X, Hutchins AP, Luo Z, Song H, Chen Y, Lai K,Yin M,Xu L, Zhou L, Chen J, Wang D, Qin B, Frampton J, Tse HF1, Pei D, Wang H, Zhang B, Esteban MA. The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters. Cell Research. 2015. 25. 80-92.

    4.Shipeng Feng, Shujie Cong, Xin Zhang, Xichen Bao, Wei Wang, Huiping Li, Zhe Wang, Guoxin Wang, Jianzhen Xu, Bowen Du, Dezhong Qu, Wei Xiong,Menghui Yin, Xiaoshuai Ren, Feifei Wang, Jianxing He and Biliang Zhang. MicroRNA-192 targeting retinoblastoma 1 (RB1) inhibits cell proliferation and induces cell apoptosis in lung cancer cells. Nucleic Acids Research 2011(39): Issue 15 Pp. 6669-6678.

    5.Xiao YH,Yin MH,Hou L,Pei Y.Direct amplification of intron-containing hairpin RNA construct from genomic DNA.Biotechniques.2006 Nov;41(5):548, 550, 552.

    6.YH Xiao,MH Yin, L Hou, M Luo, Y Pei.Asymmetric overlap extension PCR method bypassing intermediate purification and the amplification ofwild-type template in site-directed mutagenesis.Biotechnology Letters,Volume 29, Number 6: 925-930,2007

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