2005年9月-2009年7月山東大學藥學院，學士

2009年9月-2014年7月中科院上海藥物研究所藥物設計專業，博士

2015年2月-2020年7月The Johns Hopkins University School of Medicine，博士後

2020年8月至今中科院廣州生物醫藥與健康研究院化學生物學所，研究員

1.腫瘤轉錄異常關鍵靶標的動態結構-致癌功能關係研究

2.靶向致癌表觀遺傳調節蛋白和譜係特異性致癌轉錄因子的創新藥物發現

3.現有表觀遺傳藥物在腫瘤和遺傳性疾病治療中的精準應用

美國癌症研究協會(AACR)會員

2019年AACR-Get Your Rear in Gear Philadelphia Scholar in Training Award

2015年上海市研究生優秀學位論文

2012年中科院研究生國家獎學金

2011年中國科學院大學三好學生

1.Kong X^#, Chen J^#, Xie W^#, Brown S, Cai Y, Wu K, Fan D, Nie Y, Yegnasubramanian S, Tiedemann R, Tao Y, Yen R, Topper MJ, Easwaran H, Rothbart SB^*, Xia L^*, Baylin SB^*,Defining UHRF1 Domains That Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties,Cancer Cell.2019;35(4):633-648

2.Kong X^#, Liu J^#, Li L, Yue L, Zhang L, Jiang H, Xie X^*, Luo C^*,Functional interplay between the RK motif and linker segment dictates Oct4-DNA recognition,Nucleic Acids Res.2015;43(9):4381-92

3.Kong X^#, Chen L^#, Jiao L, Jiang X, Lian F, Lu J, Zhu K, Du D, Liu J, Ding H, Zhang N, Shen J, Zheng M, Chen K, Liu X, Jiang H, Luo C^*.Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2,J Med Chem.2014;57(22):9512-21

4.Ye F^#,Kong X^#, Zhang H, Liu Y, Shao Z, Jin J, Cai Y, Zhang R, Li L, Zhang YW, Liu YC, Zhang C, Xie W, Yu K, Ding H, Zhao K, Chen S, Jiang H^*, Baylin SB^*, Luo C^*.Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1,ACS Chem Biol. 2018;13(3):772-781

5.Zhu M^#, Du D^#, Hu J, Li L, Liu J, Ding H,Kong X^*, Jiang H, Chen K, Luo C^*,Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors,Acta Pharmacol Sin.2018;39(2):302-310（co-corresponding）

6.Kong X^#, Qin J^#, Li Z^#, Vultur A, Tong L, Feng E, Rajan G, Liu S, Lu J, Liang Z, Zheng M, Zhu W, Jiang H, Herlyn M, Liu H, Marmorstein R^*, Luo C^*.,Development of a novel class ofB-Raf^V600E-selective inhibitors through virtual screening and hierarchical hit optimization,Organ Biomol Chem, 2012;10:7402-17

7.Lu J^#,Kong X^#, Luo C^*, Li KK^*.Application of Epigenome-Modifying Small Molecules in Induced Pluripotent Stem Cells,Med Res Rev, 2012, May 11, DOI:10.1002/med.21265

8.Kong X^#,Ouyang S^#, Liang Z, Lu J, Chen L, Shen B, Li D, Zheng M, Li KK^*, Luo C^*, Jiang H.,Catalytic Mechanism Investigation of Lysine-Specific Demethylase 1 (LSD1): A computational study,PLoS ONE, 2011;6(9): e25444

9.Chen L^#,Kong X^#, Liang Z, Ye F, Yu K, Dai W, Wu D^*, Luo C^*, Jiang H,Theoretical study of the mechanism of proton transfer in the esterase EstB from Burkholderia gladioli,J Phys Chem B, 2011;115 (44), 13019-13025