首頁>> 中文>> 專家人才

專家人才

  • 姓名：陳奇
  • 性別：男
  • 職稱：研究員
  • 學曆：博士
  • 電話：
  • 傳真：
  • 電子郵件:chen_qi@gibh.ac.cn
  • 通訊地址廣州市黃埔區開源大道190號

    簡曆：

  • 2003-2007華東理工大學學士

    2007-2013中國科學院上海生命科學研究院博士

    2013-2021德國馬普分子生物醫學研究所及明斯特大學醫學院博士後

    研究領域：

  • 1、造血幹細胞與骨髓微環境相互作用

    2、血管在呼吸疾病與再生中的功能

    承擔科研項目情況：

    社會任職：

    獲獎及榮譽：

  • 1、2019年馬普分子生物醫學所突出工作獎

    2、2019年德國幹細胞協會年會牆報獎

    3、2016年Gordon Research Conference旅行獎

    4、2011年第七屆歐洲斑馬魚會議牆報獎

    國際學術大會口頭報告

    1、2018年Gordon Research Conference, Endothelial cell phenotypes in health and disease

    2、2018年EMBL Conference, Hematopoietic stem cells from the embryo to the aging organism

    3、2015年Dutch German joint meeting of the Molecular Cardiology

    4、2012年Kloster Seeon Angiogenesis meeting

    代表論著：

  • （1）Qi Chen#, Yang Liu#, Hyun-Woo Jeong, Martin Stehling, Van Vuong Dinh, Bin Zhou, Ralf H. Adams. Apelin+ endothelial niche cells control hematopoiesis and mediate vascular regeneration after myeloablative injury.Cell Stem Cell, 2019Dec 5;25(6):768-783.e6. doi: 10.1016/j.stem.2019.10.006.#Equalcontribution（影響因子：24.633）

    Cell Stem Cell專門評論文章: Mutualism in the Marrow 2019 Dec 5;25(6):731-733. doi: 10.1016/j.stem.2019.11.007.

    （2）Yang Liu#,Qi Chen#, Hyun-Woo Jeong, Dong Han, J？rg Fabian, Hannes Drexler, Martin Stehling, Hans R. Sch？ler, Ralf H. Adams. Dopamine signaling regulates hematopoietic stem and progenitor cell function.Blood,2021 Nov 25;138(21):2051-2065. doi: 10.1182/blood.2020010419.（封麵文章, Featured Article）# Equalcontribution(影響因子: 23.629)

    Blood專門評論文章:Dopamine motivates stem cells for reward. Blood. 2021 Nov 25;138(21):2012-2014. doi: 10.1182/blood.2021013538

    （3）Yang Liu#,Qi Chen#, Hyun-Woo Jeong#, Bong-Ihn Koh, Emma Watson, Cong Xu, Martin Stehling, Bin Zhou, Ralf H. Adams. A specialized bone marrow microenvironment for fetal haematopoiesis.Nature Communications, 2022, 13 (1327). https://doi.org/10.1038/s41467-022-28775-x(影響因子: 14.919)

    （4）Qi Chen, Hui Zhang, Yang Liu, Dagmar Zeuschner, Monica Corada, Elisabetta Dejana, Bin Zhou and Ralf H. Adams. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. (2016)Nature Communications.7:12422 doi:10.1038/ncomms12422. (影響因子: 14.919，已被引123次)

    （5）Qi Chen#, Luan Jiang#, Chun Li, Dan Hu, Ji-wen Bu, David Cai, Jiu-lin Du.Haemodynamics- Driven Developmental Pruning of Brain Vasculature in Zebrafish. (2012)PLoS Biology10(8): e1001374.#Equalcontribution(已被引125次)

    被Nature選為亮點論文：Highlight in Neurodevelopment: Low flow blood vessel pruning. Nature (2012) 488(7413): 560.

    PLoS Biology專門評論文章(2012) Pruning Brain Vasculature for Efficiency. PLoS Biol 10(8): e1001375

    （6）David Rohde, Katrien Vandoorne, I-Hsiu Lee, Jana Grune, Shuang Zhang, Cameron S. McAlpine, Maximilian J. Schloss, Ribhu Nayar, Gabriel Courties, Vanessa Frodermann, Gregory Wojtkiewicz, Lisa Honold,Qi Chen, Stephen Schmidt, Yoshiko Iwamoto, Yuan Sun, Sebastian Cremer, Friedrich F. Hoyer, Oriol Iborra-Egea, Christian Mu？oz-Guijosa, Fei Ji, Bin Zhou, Ralf H. Adams, Joshua D. Wythe, Juan Hidalgo, Hideto Watanabe, Yookyung Jung, Anja M. van der Laan, Jan J. Piek, Youmna Kfoury, Pauline A. Désogère, Claudio Vinegoni, Partha Dutta, Ruslan I. Sadreyev, Peter Caravan, Antoni Bayes-Genis, Peter Libby, David T. Scadden, Charles P. Lin, Kamila Naxerova, Filip K. Swirski & Matthias Nahrendorf. Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease.Nature Cardiovascular Research2022, 1(28–44)（創刊號論文）

    Nature專門評論文章: Cardiovascular diseases disrupt the bone-marrow niche. https://doi.org/10.1038/d41586-021-03550-y

    Nature Reviews Cardiology專門評論文章: Cardiovascular disease alters the bone marrow vasculaturehttps://doi.org/10.1038/s41569-022-00671-3

    （7）Cong Xu, Van Vuong Dinh, Kai Kruse, Hyun-Woo Jeong, Emma C Watson, Susanne Adams, Frank Berkenfeld, Martin Stehling, Seyed Javad Rasouli, Rui Fan, Rui Chen, Ivan Bedzhov,Qi Chen, Katsuhiro Kato, Mara Elena Pitulescu, Ralf H Adams. Induction of osteogenesis by bone-targeted Notch activation.eLife, 2022, Feb 4;11:e60183. doi: 10.7554/eLife.60183.

    （8）Ting-ting Liu, Xu-fei Du, Bai-bing Zhang, Hua-xing Zi, Yong Yan, Jiang-an Yin, Han Hou, Shan- ye Gu,Qi Chen, Jiu-Lin Du. Piezo1-mediated Ca2+activities regulate brain vascular pathfinding during development. (2020)Neurondoi.org/10.1016/j.neuron.2020.07.025(影響因子: 17.173)

    （9）Yang Liu, Xiao-Hui Xu,Qi Chen, Tong Wang, Cai-Yun Deng, Bao-Liang Song, Jiu-Lin Du, Zhen-GeLuo. Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development.(2013)Nature Communications. doi:10.1038/ncomms3005(影響因子: 14.919)

    （10）Yu Zhang, Bing Xu,Qi Chen, Yong Yan, Jiu-lin Du, Xufei Du. Apoptosis of Endothelial Cells Contributes to Brain Vessel Pruning of Zebrafish During Development. (2018)Front. Mol. Neurosci. 11:222. doi:10.3389/fnmol.2018.00222 (影響因子: 5.639)
Baidu
map