首頁>> 中文>> 專家人才

專家人才

  • 姓名:單永禮
  • 性別:
  • 職稱:副研究員
  • 學曆:博士
  • 電話:
  • 傳真:
  • 電子郵件:shan_yongli@gibh.ac.cn
  • 通訊地址廣州市黃埔區開源大道190號

    簡曆:

  • 2008.09-2012.06安徽大學生物科學學士

    2012.09-2018.01betway体育下载 細胞生物學博士

    2018.01-2018.08betway体育下载 助理研究員

    2018.09-2021.01南方醫科大學南方醫院博士後

    2021.01至今betway体育下载 副研究員

    研究領域:

  • 1.人多能幹細胞幹性維持與譜係分化的研究

    2.人胎盤發育及胎盤疾病建模研究。

    承擔科研項目情況:

  • 1.國家自然科學基金麵上項目(2022

    2.國家自然科學基金青年項目(2018

    3.中國博士後科學基金麵上項目(2019

    4.廣東省自然科學基金麵上項目(2020

    5.廣州市科技計劃項目科學研究計劃一般項目(2019

    社會任職:

    獲獎及榮譽:

    代表論著:

  • 1. Wei Yanxing, Wang Tianyu, Ma Lishi, Zhang Yanqi, Zhao Yuan, Lye Kathryn, Xiao Lu, Chen Chunlin, Wang Zhijian, Ma Yanlin, Zhou Xiaohua, Sun Fei, Li Weili, Dunk Caroline, Li Siliang, Nagy Andras, Yu Yanhong, Pan Guangjin*, Lye J Stephen*,Shan Yongli*. Efficient Derivation of Human Trophoblast Stem Cells from Primed Pluripotent Stem Cells. Science Advances, 2021, 7: eabf4416.

    2.Shan Yongli#, Zhang Yanqi#, Zhao Yuan#, Wang Tianyu, Zhang Jingyuan, Yao Jiao, Ma Ning, Liang Zechuan, Huang Wenhao, Huang Ke, Zhang Tian, Su Zhenghui, Chen Qianyu, Zhu Yanling, Wu Chuman, Zhou Tiancheng, Sun Wei, Wei Yanxing, Zhang Cong, Li Chenxu, Su Shuquan, Liao Baojian, Zhong Mei, Zhong Xiaofen, Nie Jinfu, Pei Duanqing, Pan Guangjin*. JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells.Nature Communications, 2020, 11 (1): 382.

    3.Shan Yongli#, Liang Zechuan#, Xing Qi, Zhang Tian, Wang Bo, Tian Shulan, Huang Wenhao, Zhang Yanqi, Yao Jiao, Zhu Yanling, Huang Ke, Liu Yujian, Wang Xiaoshan, Chen Qianyu, Zhang Jian, Shang Bizhi, Li Shengbiao, Shi Xi, Liao Baojian, Zhang Cong, Lai Keyu, Zhong Xiaofen, Shu Xiaodong, Wang Jinyong, Yao Hongjie, Chen Jiekai, Pei Duanqing and Pan Guangjin*. (2017). PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naive ESCs.Nature Communications8: 672.

    4.Wei Yanxing#, Xiao Lu#, Ma Lishi, Wang Zhijian, Huang Liping, Li Huiying, Pan Guangjin, Lye J. Stephen,Shan Yongli*. Protocol to derive human trophoblast stem cells directly from primed pluripotent stem cells.STAR Protocols, 2022, 3: 101638.

    5.Long Bong#,Shan Yongli#, Sun Yanling#, Wang Tianyu, Li Xudong, Huang Ke, Zhang Wenwen, He Yi, Wen Ruijuan, Li Yuhang, Mai Yuchan, Feng Yashu, Zhang Tian, Kang Baoqiang, Zhang Cong, Zhu Yanling, Gu Jiaming, Liu Jiajun, Zhang Xiangzhong*, Pan Guangjin*. Vitamin C promotes anti-leukemia of DZNep in acute myeloid leukemia.Biochimica et Biophysica Acta-MolecularBasis of Disease, 2022, 1868: 166357.

    6.Zhao Yuan#, Wang Tianyu#, Zhang Yanqi#, Shi Liang, Zhang Cong, Zhang Jingyuan, Yao Jiao, Chen Qianyu, Zhong Xiaofen, Wei Yanxing,Shan Yongli*, Pan Guangjin*. Coordination of EZH2 and SOX2 specifies human neural fate decision.Cell Regeneration, 2021, 10: 30.

    7.Xiao Lu#, Ma Lishi#, Wang Zhijian, Yu Yanhong, Lye J. Stephen,Shan Yongli*, Wei Yanxing*. Deciphering a distinct regulatory network of TEAD4, CDX2 and GATA3 in humans for trophoblast transition from embryonic stem cells.Biochimica et Biophysica Acta-Molecular Cell Research, 2020, 1867: 118736.

    8. Ma Ning#,Shan Yongli#, Liao Baojian#, Kong Guanyi#, Wang Cheng, Huang Ke, Zhang Hui, Cai Xiujuan, Chen Shubin, Pei Duanqing, Chen Nansheng*, Pan Guangjin*. Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in beta-Thalassemia Induced Pluripotent Stem Cells (iPSCs).Journal of Biological Chemisrty, 2015, 290(19):12079-89.

Baidu
map